DEFB1 gene 5′ untranslated region (UTR) polymorphisms in inflammatory bowel diseases
نویسندگان
چکیده
Valentina Zanin, Ludovica Segat, Anna Monica Bianco, Lara Padovan, Nathalia de Alencar Cunha Tavares, Sergio Crovella I University of Trieste, Institute for Maternal and Child Health – IRCCS ‘‘Burlo Garofolo’’, Trieste, Italy. II Institute for Maternal and Child Health – IRCCS ‘‘Burlo Garofolo’’Trieste, Italy. III Federal University of Pernambuco, Laboratory of Immunopathology Keizo Asami (LIKA), Recife/PE, Brazil. IV Institute for Maternal and Child Health IRCCS ‘‘Burlo Garofolo’’, Trieste, University of Trieste, Italy.
منابع مشابه
Characterization of single nucleotide polymorphism in the 5'-untranslated region (5'-UTR) of Lactoferrin gene and its association with reproductive parameters and uterine infection in dairy cattle
Uterine infection is one of the reproductive diseases that can have disturbing postpartum uterine health in cattle. Therefore, identification of resistant genotypes to uterine infection is important. Lactoferrin (LF) is one of the major antimicrobial compounds in the normal uterine discharges of cows. We hypothesized that allelic diversity in LF gene may contribute to susceptibility or resistan...
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The human beta defensin 1 (hBD-1) antimicrobial peptide is a member of the innate immune system known to act in the first line of defence against microorganisms, including viruses such as human papillomavirus (HPV). In this study, five functional polymorphisms (namely g-52G>A, g-44C>G and g-20G>A in the 5'UTR and c.*5G>A and c.*87A>G in the 3'UTR) in the DEFB1 gene encoding for hBD-1 were analy...
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عنوان ژورنال:
دوره 67 شماره
صفحات -
تاریخ انتشار 2012